Science

Biofilm: the invisible factor.

While some bacteria play an important role in body functions, others have negative effects. Oral biofilm is a complex community of microorganisms that can lead to caries, gingivitis and periodontitis.

Not just a local problem

Research has linked oral bacteria and inflammation to cardiovascular disease, diabetes and respiratory infections.

The mouth as a gateway

Scientific research has established a close link between oral health and overall well-being, with far-reaching effects on the heart, the respiratory system and potentially even Alzheimer’s disease. By harnessing this connection, we open the door to a new era of prevention.

“Detection starts once the disease has already developed and the patient is already in pain.”

The problem

Prevention is still subjective and time-consuming.

Dental hygiene is recurring and high-frequency, yet this clinical workflow is missing a consistent, scalable measurement layer.

  • Invisible to the naked eye

    Biofilm drives caries and periodontitis, yet it remains invisible to the naked eye. Plaque mapping often depends on disclosure, visual judgement and manual scoring.

  • A 60-year-old staining method

    Disclosing agents are imprecise, leave residue and limit patients’ understanding. The method is time-consuming, unpopular with patients and difficult to scale digitally.

  • No comparable index

    Assessment is subjective and documentation is manual. Without objective data, prevention cannot be measured, compared or improved systematically over time.

What we address

From repair to prevention.

Through artificial intelligence and technological precision, we aim to shift dentistry away from a repair-first mindset towards a more proactive, preventive and data-driven approach to oral health.

  • 01

    Visible

    Making the invisible visible: the biofilm on every tooth surface.

  • 02

    Measurable

    Objective data instead of subjective assessment.

  • 03

    Early

    Potential risks identified before they develop into disease.

Clinical validation

Two university studies. One evidence strategy.

90 planned participants across complementary protocols evaluating biofilm measurement, diagnostic accuracy and clinical usability.

University Dental Clinic Vienna

Under ethics review

50planned participants

Prof. Markus Laky, MSc

Clinical comparator

Rustogi Modified Navy Plaque Index (RMNPI)

AI plaque-level assessment vs. clinician scoring

Sigmund Freud Private University

Ethics approved

40planned participants

Prof. Barbara Cvikl

Clinical comparator

Mira-2-Ton plaque-disclosing reference

Sensitivity, specificity and ROC-AUC

Complementary evidence

The Sigmund Freud Private University study also measures examination time, comfort, preference and motivation.

Study designs as submitted. Ethics status as of October 2026. Results are pending.